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If you’re living with diabetes, chances are you’ve felt that familiar burning, tingling, or numbness in your feet—especially at night. This uncomfortable sensation is called diabetic neuropathy, and in simple terms, it develops when high blood sugar levels gradually damage the nerves that help you feel temperature, touch, and pain.
Because the nerves in the feet are some of the smallest and farthest from the heart, they’re often the first to suffer. For many people, the symptoms become even more noticeable here in Georgia, where the warmer, humid climate can make swelling, irritation, and skin dryness worse.
These symptoms can interfere with everything from sleep to mobility, and the frustration is very real.
That’s why effective foot care is not just recommended—it’s essential. The right topical cream can soothe irritated nerves, moisturize dry skin, and provide meaningful comfort throughout the day.
Over time, elevated glucose levels prevent nerves from receiving the oxygen and nutrients they need. This leads to nerve fiber breakdown, misfiring pain signals, and the burning or numbness many patients feel.
Diabetes can narrow and stiffen blood vessels, limiting healthy blood flow. The feet—being the farthest distance from the heart—are usually the first to show symptoms.
Chronic inflammation can irritate nerves and surrounding tissues, intensifying discomfort and sensitivity.
Nerves in the hands and feet (called peripheral nerves) are more vulnerable because they’re long, delicate, and rely heavily on strong blood flow. When circulation declines, these nerves struggle first, and neuropathy begins from the “bottom up.”
OTC creams can be helpful when:
But creams alone are not enough when:
In these cases, professional evaluation is essential. At Medici Orthopaedics & Spine, we look deeper—identifying circulation issues, nerve damage patterns, and overall foot health to create a personalized plan far beyond what OTC products can offer.
These ingredients help calm burning, tingling, and sharp nerve pain.
A topical anesthetic that temporarily “numbs” the area by blocking overactive nerve signals. Great for fast, targeted relief.
Derived from chili peppers, capsaicin reduces pain by depleting “substance P”—a neurotransmitter that delivers pain signals. It takes consistent use but can offer long-term benefits.
Provides a cooling sensation that distracts the brain from deeper nerve discomfort. Helpful for flare-ups and nighttime pain.
These ingredients support nerve health and reduce inflammation.
A powerful antioxidant shown to improve nerve function and reduce burning sensations, especially in people with diabetes.
Essential for nerve repair. Topical B12 can help slow nerve deterioration over time.
CBD may reduce nerve inflammation and provide a calming effect without psychoactive properties.
People with diabetic neuropathy often have dry, fragile skin prone to cracking and infection. These ingredients strengthen and hydrate the skin.
Softens thickened skin and draws moisture in—excellent for calluses and dryness.
Rich in fatty acids that help repair the skin barrier and retain moisture.
Attracts water to the skin, improving hydration and elasticity.
Georgia’s warm, humid climate affects how creams feel and absorb. Look for:
Lidocaine temporarily blocks nerve signals, offering rapid relief from burning or sharp pain—often within minutes.
Widely available at CVS, Walgreens, and Publix across Georgia. Many patients prefer Aspercreme Lidocaine or LidoRx for reliability.
It reduces overactive nerve signals by depleting substances involved in transmitting pain.
A warm or mild burning sensation during early applications is normal and usually fades with regular use.
Patients with cracked skin, open wounds, or extremely sensitive skin.
ALA reduces oxidative stress—the underlying contributor to nerve damage in diabetes.
Improves nerve conduction and decreases burning pain over time.
Top products include Nerve Renew Cream, available online and in some Georgia wellness stores.
Dry, cracked skin increases the risk of infection, which is especially dangerous for diabetic patients.
Even though Georgia is humid, air conditioning and footwear dryness can still cause dehydration in the feet.
Popular options include Eucerin Advanced Repair and Urea 20% Cream.
Menthol provides instant cooling that can soothe nerve flare-ups.
CBD may help reduce nerve and joint inflammation, offering relief without traditional medications.
These products are easily found in Georgia pharmacies and specialty wellness shops.
These retailers carry most OTC neuropathy creams, especially lidocaine, urea, and capsaicin options.
Better for specialty items like ALA creams, CBD blends, or dermatologist-recommended formulations.
Most neuropathy creams can be applied 1–3 times per day, depending on the ingredients:
Fast-absorbing, non-greasy creams work best during the day so they don’t affect your mobility or stain footwear.
This is a great time for deeper hydration or nerve-calming ingredients. Many patients notice improved sleep when they apply creams before bed.
Compression socks can improve circulation, but they should only be used:
Diabetic neuropathy can feel overwhelming—especially when burning, tingling, or numbness becomes part of everyday life. But the truth is this: neuropathy is manageable, and you have more treatment options than you may realize.
Top-rated foot creams can provide meaningful comfort, soothe irritated nerves, and protect sensitive skin. But while they’re helpful tools, they’re rarely the full solution. Long-term relief often requires a deeper look at circulation, nerve health, and the underlying causes of your symptoms.
At Medici Orthopaedics & Spine, we take the time to understand the whole picture. Our team offers innovative, personalized, and least-invasive treatments designed not only to ease symptoms—but to help restore your comfort, mobility, and overall quality of life. You deserve care that sees you, supports you, and gives you hope.
At Medici, you’re more than your MRI.
We take time to hear your story, understand your pain, and create a plan that actually works for you.

Our team delivers specialist care at convenient locations across Metro Atlanta:
Get expert tips on injury recovery, pain relief, joint health, and movement strategies—straight from our Fellowship-Trained team.